ACVYBRA^® maintains the same dosage and administration as the injection method your patients are used to³

Acvybra^® device: similar PFS,
optimized user experience³

• Wings to ease activation & facilitate handling for patients, especially those with reduced grip
• Needle protection – high force needed to break the device after activation
• High resistance to incidental activation
  (i.e. while traveling)
• Smaller needle vs reference product (29G vs 27G)
• Passive safety system activated upon injection completion

Convenient injection
once every 6 Months:³

• 60 mg of denosumab in a single subcutaneous injection.
• No dose adjustment is required in patients with renal impairment.

Storage:³

• Store in a refrigerator
  (2 °C - 8 °C).
• Do not freeze.
• Keep the pre-filled syringe in the outer carton in order to protect from light.